منابع مشابه
Silymarin nanoparticle prevents paracetamol-induced hepatotoxicity
Silymarin (Sm) is a polyphenolic component extracted from Silybum marianum. It is an antioxidant, traditionally used as an immunostimulant, hepatoprotectant, and dietary supplement. Relatively recently, Sm has proved to be a valuable chemopreventive and a useful antineoplastic agent. Medical success for Sm is, however, constrained by very low aqueous solubility and associated biopharmaceutical ...
متن کاملPotential protective effect of honey against paracetamol-induced hepatotoxicity.
BACKGROUND Paracetamol overdose causes severe hepatotoxicity that leads to liver failure in both humans and experimental animals. The present study investigates the protective effect of honey against paracetamol-induced hepatotoxicity in Wistar albino rats. We have used silymarin as a standard reference hepatoprotective drug. METHODS Hepatoprotective activity was assessed by measuring biochem...
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Protective action of Livol (a herbal formulation) against paracetamol induced experimental hepatotoxicity was observed in dog. Increased values of serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, serum total cholesterol and its fractions, globulin, icterus index, prothrombin time and bromosulphalein retention by paracetamol (250 mg/kg, once orally) were decrease...
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Liaqat HUSSAIN, Javaria IKRAM, Kanwal REHMAN, Muhammad TARIQ, Muhammad IBRAHIM, Muhammad Sajid Hamid AKASH* College of Pharmacy, Government College University Faisalabad, Faisalabad, Pakistan Institute of Pharmacology, Toxicology, and Biochemical Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P.R. China Department of Applied Chemistry, Faculty of Science and T...
متن کاملProtective Activity in Paracetamol Induced Hepatotoxicity and Antioxidant Potential from Lippia nodiflora (Verbenaceae) in Rats
This study was designed to evaluate the hepatoprotective and antioxidant activity of methanol extract of Lippia nodiflora (MELN) in acute experimental liver injury induced by paracetamol (750mg/kg, b.w). MELN at the doses of 200 and 400mg/kg, p.o was administered for 7 days and biochemical parameters such as serum glutamate oxaloacetate transaminase (SGOT), glutamate pyruvate transamina...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 2005
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.2005.076836